The TIM22 complex mediates the import of sideroflexins and is required for efficient mitochondrial one-carbon metabolism
نویسندگان
چکیده
Proteomic profiling of Sengers patient fibroblasts and AGK knockout models identifies remodeling the mitochondrial proteome, including one-carbon metabolism enzymes, inner membrane serine transporters, sideroflexins, Complex I subunits assembly factors.
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2021
ISSN: ['1059-1524', '1939-4586']
DOI: https://doi.org/10.1091/mbc.e20-06-0390